Lipinski, Christopher : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (105)
Les plus populaires
Liste
- Liste
- Tableau

1

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A. Lipinski, Franco Lombardo, Beryl W. Dominy, Paul J. Feeney

Journal:

Advanced Drug Delivery Reviews

Année:

1997

Langue:

english

Fichier:

PDF, 2.40 MB

english, 1997

2

Lead- and drug-like compounds: the rule-of-five revolution

Christopher A. Lipinski

Journal:

Drug Discovery Today: Technologies

Année:

2004

Langue:

english

Fichier:

PDF, 114 KB

english, 2004

3

Drug-like properties and the causes of poor solubility and poor permeability

Christopher A. Lipinski

Journal:

Journal of Pharmacological and Toxicological Methods

Année:

2000

Langue:

english

Fichier:

PDF, 531 KB

english, 2000

4

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Lipinski, Christopher A., Lombardo, Franco, Dominy, Beryl W., Feeney, Paul J.

Journal:

Advanced Drug Delivery Reviews

Année:

2012

Langue:

english

Fichier:

PDF, 293 KB

english, 2012

5

The rule of five should not impede anti-parasitic drug development

McKerrow, James H., Lipinski, Christopher A.

Journal:

International Journal for Parasitology Drugs and Drug Resistance

Année:

2017

Langue:

english

Fichier:

PDF, 144 KB

english, 2017

6

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

Christopher A Lipinski, Franco Lombardo, Beryl W Dominy, Paul J Feeney

Journal:

Advanced Drug Delivery Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 157 KB

english, 2001

7

Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions

Lipinski, Christopher A.

Journal:

Advanced Drug Delivery Reviews

Année:

2016

Langue:

english

Fichier:

PDF, 655 KB

english, 2016

8

Agonist-induced activation of the S1P receptor 2 constitutes a novel osteoanabolic therapy for the treatment of osteoporosis in mice

Weske, Sarah, Vaidya, Mithila, von Wnuck Lipinski, Karin, Keul, Petra, Manthe, Kristina, Burkhart, Christoph, Haberhauer, Gebhard, Heusch, Gerd, Levkau, Bodo

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 749 KB

english, 2019

9

The anti-intellectual effects of intellectual property

Christopher A Lipinski

Journal:

Current Opinion in Chemical Biology

Année:

2006

Langue:

english

Fichier:

PDF, 87 KB

english, 2006

10

Navigating chemical space for biology and medicine

Lipinski, Christopher, Hopkins, Andrew

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 386 KB

english, 2004

11

pKa, Log P and MedChem CLOGP Fragment Values of Acidic Heterocyclic Potential Bioisosteres

Christopher A. Lipinski, Eugene F. Fiese, Robert J. Korst

Journal:

Molecular Informatics

Année:

1991

Langue:

english

Fichier:

PDF, 714 KB

english, 1991

12

Feasibility and Initial Efficacy of a Comprehensive School-Based Intervention for High-Functioning Autism Spectrum Disorders

Lopata, Christopher, Thomeer, Marcus L., Volker, Martin A., Lee, Gloria K., Smith, Tristram H., Smith, Rachael A., Mcdonald, Christin A., Rodgers, Jonathan D., Lipinski, Alanna M., Toomey, Jennifer A.

Journal:

Psychology in the Schools

Année:

2012

Langue:

english

Fichier:

PDF, 83 KB

english, 2012

13

Teachers’, LGBTQ Students’, and Student Allies’ Perceptions of Bullying of Sexually-Diverse Youth

Crothers, Laura M., Kolbert, Jered B., Berbary, Cassandra, Chatlos, Suzannah, Lattanzio, Latitia, Tiberi, Amy, Wells, Daniel S., Bundick, M. J., Lipinski, John, Meidl, Christopher

Journal:

Journal of Aggression Maltreatment & Trauma

Année:

2017

Langue:

english

Fichier:

PDF, 1.36 MB

english, 2017

14

Development of an inducible anti-VEGF rAAV gene therapy strategy for the treatment of wet AMD

Reid, Christopher A., Nettesheim, Emily R., Connor, Thomas B., Lipinski, Daniel M.

Journal:

Scientific Reports

Année:

2018

Langue:

english

Fichier:

PDF, 7.13 MB

english, 2018

15

Brief Report: Examination of Sex-Based Differences in ASD Symptom Severity Among High-Functioning Children with ASD Using the SRS-2

Rodgers, Jonathan D., Lodi-Smith, Jennifer, Donnelly, James P., Lopata, Christopher, McDonald, Christin A., Thomeer, Marcus L., Lipinski, Alanna M., Nasca, Brian C., Booth, Adam J.

Journal:

Journal of Autism and Developmental Disorders

Année:

2018

Langue:

english

Fichier:

PDF, 830 KB

english, 2018

16

Team strategies and tools to enhance performance and patient safety training: The effect of training on both nursing staff perceptions regarding physician behaviors and patient satisfaction scores in the ED

Brand, Shari I., M. Slee, Kristen, Chang, Yu-Hui, Cheng, Meng-Ru, A. Lipinski, Christopher, R. Arnold, Rick, J.Traub, Stephen

Journal:

Journal of Hospital Administration

Année:

2015

Langue:

english

Fichier:

PDF, 575 KB

english, 2015

17

High throughput in vivo phenotypic screening for drug repurposing: Discovery of MLR-1023 a novel insulin sensitizer and novel Lyn kinase activator with clinical proof of concept

Lipinski, Christopher A., Reaume, Andrew G.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2020

Langue:

english

Fichier:

PDF, 1009 KB

english, 2020

18

Elevated expression of ICAM1 (CD54) and minimal expression of LFA3 (CD58) in epstein-barr-virus-positive nasopharyngeal carcinoma cells

Pierre Busson, Qin Zhang, Jean-Michel Guillon, Christopher D. Gregory, Lawrence S. Young, Bernard Clausse, Marc Lipinski, Alan B. Rickinson, Thomas Tursz

Journal:

International Journal of Cancer

Année:

1992

Langue:

english

Fichier:

PDF, 790 KB

english, 1992

19

Single-mode compound retrieval for QSAR, QSPR data sets, and batch mode exact structure searching

Christopher A. Lipinski

Journal:

Journal of Pharmaceutical Sciences

Année:

2002

Langue:

english

Fichier:

PDF, 52 KB

english, 2002

20

Medicinal chemistry of aldose reductase inhibitors

Eric R. Larson, Christopher A. Lipinski, Reinhard Sarges

Journal:

Medicinal Research Reviews

Année:

1988

Langue:

english

Fichier:

PDF, 1.57 MB

english, 1988

21

Olfactory and Gustatory Hallucinations Presenting as Partial Status Epilepticus Because of Glioblastoma Multiforme

Dan J. Capampangan, Matthew T. Hoerth, Joseph F. Drazkowski, Christopher A. Lipinski

Journal:

Annals of Emergency Medicine

Année:

2010

Langue:

english

Fichier:

PDF, 378 KB

english, 2010

22

Synthesis and antitubercular activity of 7-(R)- and 7-(S)-methyl-2-nitro-6-(S)-(4-(trifluoromethoxy)benzyloxy)-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazines, analogues of PA-824

Xiaojin Li, Ujjini H. Manjunatha, Michael B. Goodwin, John E. Knox, Christopher A. Lipinski, Thomas H. Keller, Clifton E. Barry III, Cynthia S. Dowd

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 486 KB

english, 2008

23

The utility of the coupling reaction between propargyl grignard reagent and allylic halides for the synthesis of acetylenes

Robert E. Ireland, Marcia I. Dawson, Christopher A. Lipinski

Journal:

Tetrahedron Letters

Année:

1970

Langue:

english

Fichier:

PDF, 200 KB

english, 1970

24

Vertebrobasilar Distribution Stroke Mimicking Transtentorial Herniation

Christopher A Lipinski, Eric R Swanson

Journal:

Annals of Emergency Medicine

Année:

1998

Langue:

english

Fichier:

PDF, 47 KB

english, 1998

25

Feasibility of external cranial cooling during out-of-hospital cardiac arrest

Clifton W. Callaway, Scott C Tadler, Laurence M Katz, Christopher L Lipinski, Eric Brader

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 182 KB

english, 2002

26

Normoxic ventilation during resuscitation and outcome from asphyxial cardiac arrest in rats

Christopher A Lipinski, Shawn D Hicks, Clifton W Callaway

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 417 KB

english, 1999

27

Physical parameters for brian uptake: optimizing log P, log D and pKa of T H A

Manoj C. Desai, Peter F. Thadeio, Christopher A. Lipinski, Dane R. Liston, Robin W. Spencer, Ian H. Williams

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1991

Langue:

english

Fichier:

PDF, 276 KB

english, 1991

28

Structure of the sialic acid-containing O-specific polysaccharide from Salmonella enterica serovar Toucra O48 lipopolysaccharide

Andrzej Gamian, Christopher Jones, Tomasz Lipiński, Agnieszka Korzeniowska-Kowal, Neil Ravenscroft

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 711 KB

english, 2000

29

Geldanamycin Provides Posttreatment Protection Against Glutamate-Induced Oxidative Toxicity in a Mouse Hippocampal Cell Line

Nianqing Xiao, Clifton W. Callaway, Christopher A. Lipinski, Shawn D. Hicks, Donald B. DeFranco

Journal:

Journal of Neurochemistry

Année:

1999

Langue:

english

Fichier:

PDF, 233 KB

english, 1999

30

Acidic isostere design: Synthetic strategies and recent progress in understanding electronic properties and metabolic stability

Christopher A. Lipinski, Bert L. Chenard

Journal:

Pest Management Science

Année:

1990

Langue:

english

Fichier:

PDF, 630 KB

english, 1990

31

Extended survival of Pyk2 or FAK deficient orthotopic glioma xenografts

Christopher A. Lipinski, Nhan L. Tran, Carole Viso, Jean Kloss, Zhongbo Yang, Michael E. Berens, Joseph C. Loftus

Journal:

Journal of Neuro-Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 414 KB

english, 2008

32

Structural analysis of the Lactobacillus rhamnosus strain KL37C exopolysaccharide

Tomasz Lipiński, Christopher Jones, Xavier Lemercinier, Agnieszka Korzeniowska-Kowal, Magdalena Strus, Jacek Rybka, Andrzej Gamian, Piotr B Heczko

Journal:

Carbohydrate Research

Année:

2003

Langue:

english

Fichier:

PDF, 206 KB

english, 2003

33

Context conditioning and extinction in humans: differential contribution of the hippocampus, amygdala and prefrontal cortex

Simone Lang, Alexander Kroll, Slawomira J. Lipinski, Michèle Wessa, Stephanie Ridder, Christoph Christmann, Lothar R. Schad, Herta Flor

Journal:

European Journal of Neuroscience

Année:

2009

Langue:

english

Fichier:

PDF, 537 KB

english, 2009

34

Not all quiet on the noise front

McCullagh, Emma, Farlow, Justin, Fuller, Christopher, Girard, Juliet, Lipinski-Kruszka, Joanna, Lu, Dan, Noriega, Thomas, Rollins, Geoffrey, Spitzer, Russell, Todhunter, Michael

Journal:

Nature Chemical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 14.22 MB

english, 2009

35

A crowdsourcing evaluation of the NIH chemical probes

Bologa, Cristian G, Boyer, Scott, Oprea, Tudor I, Curpan, Ramona F, Glen, Robert C, Hopkins, Andrew L, Lipinski, Christopher A, Marshall, Garland R, Martin, Yvonne C, Ostopovici-Halip, Liliana

Journal:

Nature Chemical Biology

Année:

2009

Langue:

english

Fichier:

PDF, 554 KB

english, 2009

36

Erratum: A crowdsourcing evaluation of the NIH chemical probes

Oprea, Tudor I, Bologa, Cristian G, Boyer, Scott, Curpan, Ramona F, Glen, Robert C, Hopkins, Andrew L, Lipinski, Christopher A, Marshall, Garland R, Martin, Yvonne C, Ostopovici-Halip, Liliana

Journal:

Nature Chemical Biology

Année:

2009

Fichier:

PDF, 39 KB

2009

37

Antitumor immune responses mediated by adenoviral GDEPT using nitroreductase/CB1954 is enhanced by high-level coexpression of heat shock protein 70

Djeha, Hakim A, Todryk, Stephen M, Pelech, Steven, Wrighton, Christopher J, Irvine, Alistair S, Mountain, Andrew, Lipinski, Kai S

Journal:

Cancer Gene Therapy

Année:

2005

Langue:

english

Fichier:

PDF, 312 KB

english, 2005

38

Bioisosteric prototype design of biaryl imidazolyl and triazolyl competitive histamine H2-receptor antagonists

Lipinski, Christopher A., LaMattina, John L., Oates, P. J.

Journal:

Journal of Medicinal Chemistry

Année:

1986

Langue:

english

Fichier:

PDF, 1.29 MB

english, 1986

39

N-chlorination of dilantin and sorbinil

Christopher A. Lipinski, Jon Bordner, Garth C. Butterfield, Lilian C. Marinovic

Journal:

Journal of Heterocyclic Chemistry

Année:

1990

Fichier:

PDF, 586 KB

1990

40

Dünnschichtchromatographischer Nachweis von Acesulfam, Saccharin und Cyclamat*

Gert-Wolfhard von Rymon Lipinski, Hans-Christoph Brixius

Journal:

European Food Research and Technology

Année:

1979

Langue:

german

Fichier:

PDF, 108 KB

german, 1979

41

Beautiful Biology But Bad Chemistry: Recognizing Chemistry Problems Earlier Rather Than Later

Christopher Lipinski

Journal:

Antiviral Research

Année:

2009

Langue:

english

Fichier:

PDF, 69 KB

english, 2009

42

Crack-free BaTiO3 films on Si with SiO2, MgO, or Al2O3 buffer layers

Lipinsky, Thomas, Schubert, Juergen, Buchal, Christoph

Journal:

Journal of the Optical Society of America B

Année:

2005

Langue:

english

Fichier:

PDF, 133 KB

english, 2005

43

Critical role of the FERM domain in Pyk2 stimulated glioma cell migration

Christopher A. Lipinski, Nhan L. Tran, Andrea Dooley, Yuan-Ping Pang, Carole Rohl, Jean Kloss, Zhongbo Yang, Wendy McDonough, David Craig, Michael E. Berens, Joseph C. Loftus

Journal:

Biochemical and Biophysical Research Communications

Année:

2006

Langue:

english

Fichier:

PDF, 930 KB

english, 2006

44

An improved preparation and use of 2-bromoacetoacetaldehyde in a new synthesis of 2-substituted-4-acetylimidazoles

Lipinski, Christopher A., Blizniak, Thaddeus E., Craig, Rebecca H.

Journal:

Journal of Organic Chemistry

Année:

1984

Langue:

english

Fichier:

PDF, 771 KB

english, 1984

45

Pseudosymmetry and bioisosterism in biaryl pyridyl competitive histamine H2-receptor antagonists

Lipinski, Christopher A., LaMattina, John L., Hohnke, Lyle A.

Journal:

Journal of Medicinal Chemistry

Année:

1985

Langue:

english

Fichier:

PDF, 1.15 MB

english, 1985

46

Quantitative Structure−Activity Relationships among Macrolide Antibacterial Agents: In Vitro and in Vivo Potency against Pasteurella multocida

McFarland, James W., Berger, Cynthia M., Froshauer, Susan A., Hayashi, Shigeru F., Hecker, Scott J., Jaynes, Burton H., Jefson, Martin R., Kamicker, Barbara J., Lipinski, Christopher A., Lundy, Kristi

Journal:

Journal of Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 128 KB

english, 1997

47

Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis

Ekins, Sean, Kaneko, Takushi, Lipinski, Christopher A., Bradford, Justin, Dole, Krishna, Spektor, Anna, Gregory, Kellan, Blondeau, David, Ernst, Sylvia, Yang, Jeremy, Goncharoff, Nicko, Hohman, Moses

Journal:

Molecular BioSystems

Année:

2010

Langue:

english

Fichier:

PDF, 1.50 MB

english, 2010

48

2-Amino- and 2-guanidino-4-thiazolylpyrimidines

Christopher A. Lipinski, Rebecca H. Craig, Roger B. Wright

Journal:

Journal of Heterocyclic Chemistry

Année:

1985

Fichier:

PDF, 325 KB

1985

49

Drug repurposing

Christopher A. Lipinski

Journal:

Drug Discovery Today: Therapeutic Strategies

Année:

2011

Langue:

english

Fichier:

PDF, 97 KB

english, 2011

50

[Annual Reports in Computational Chemistry] Volume 1 || Capter 11 Filtering in Drug Discovery

Lipinski, Christopher A.

Année:

2005

Langue:

english

Fichier:

PDF, 143 KB

english, 2005